Interruption of Multiple Cellular Processes in HT-29 Epithelial Cells by Pseudomonas aeruginosa Exoenzyme S

Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced by the opportunistic pathogen Pseudomonas aeruginosa, is directly translocated into eukaryotic cells by bacterial contact. Within the cell, ExoS ADP-ribosylates the cell signaling protein Ras and causes inhibition of DNA synthesis and alteratio...

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Bibliografiske detaljer
Main Authors: Olson, Joan C., Fraylick, Jennifer E., McGuffie, Eileen M., Dolan, Katherine M., Yahr, Timothy L., Frank, Dara W., Vincent, Timothy S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Molecular and Cellular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96591/
https://ncbi.nlm.nih.gov/pubmed/10338490
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