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Interruption of Multiple Cellular Processes in HT-29 Epithelial Cells by Pseudomonas aeruginosa Exoenzyme S

Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced by the opportunistic pathogen Pseudomonas aeruginosa, is directly translocated into eukaryotic cells by bacterial contact. Within the cell, ExoS ADP-ribosylates the cell signaling protein Ras and causes inhibition of DNA synthesis and alteratio...

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Publicado en:Infect Immun
Autores principales: Olson, Joan C., Fraylick, Jennifer E., McGuffie, Eileen M., Dolan, Katherine M., Yahr, Timothy L., Frank, Dara W., Vincent, Timothy S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.2847-2854.1999
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