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Platelet-Activating Factor Induces Nitric Oxide Synthesis in Trypanosoma cruzi-Infected Macrophages and Mediates Resistance to Parasite Infection in Mice

Trypanosoma cruzi replicates in nucleated cells and is susceptible to being killed by gamma interferon-activated macrophages through a mechanism dependent upon NO biosynthesis. In the present study, the role of platelet-activating factor (PAF) in the induction of NO synthesis and in the activation o...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Aliberti, Júlio C. S., Machado, Fabiana S., Gazzinelli, Ricardo T., Teixeira, Mauro M., Silva, João S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.2810-2814.1999
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