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Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes.

Host resistance to infection by Trypanosoma cruzi is dependent on both natural and acquired immune responses. During the first week of infection in mice, NK cell-derived gamma interferon (IFN-gamma) is involved in controlling intracellular parasite replication, mainly through the induction of NO bio...

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Detalhes bibliográficos
Main Authors: Aliberti, J C, Cardoso, M A, Martins, G A, Gazzinelli, R T, Vieira, L Q, Silva, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC174023/
https://ncbi.nlm.nih.gov/pubmed/8675294
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