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Severe Impairment in Early Host Defense against Candida albicans in Mice Deficient in Myeloperoxidase

Myeloperoxidase (MPO) catalyzes the reaction of hydrogen peroxide with chloride ion to produce hypochlorous acid (HOCl), which is used for microbial killing by phagocytic cells. Despite the important role of MPO in host defense, however, MPO deficiency is relatively common in humans, and most of the...

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Bibliografske podrobnosti
izdano v:Infect Immun
Principais autores: Aratani, Yasuaki, Koyama, Hideki, Nyui, Sei-ichiro, Suzuki, Kazuo, Kura, Fumiaki, Maeda, Nobuyo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10085024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.4.1828-1836.1999
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