Severe Impairment in Early Host Defense against Candida albicans in Mice Deficient in Myeloperoxidase

Myeloperoxidase (MPO) catalyzes the reaction of hydrogen peroxide with chloride ion to produce hypochlorous acid (HOCl), which is used for microbial killing by phagocytic cells. Despite the important role of MPO in host defense, however, MPO deficiency is relatively common in humans, and most of the...

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Autors principals: Aratani, Yasuaki, Koyama, Hideki, Nyui, Sei-ichiro, Suzuki, Kazuo, Kura, Fumiaki, Maeda, Nobuyo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96534/
https://ncbi.nlm.nih.gov/pubmed/10085024
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