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Severe Impairment in Early Host Defense against Candida albicans in Mice Deficient in Myeloperoxidase

Myeloperoxidase (MPO) catalyzes the reaction of hydrogen peroxide with chloride ion to produce hypochlorous acid (HOCl), which is used for microbial killing by phagocytic cells. Despite the important role of MPO in host defense, however, MPO deficiency is relatively common in humans, and most of the...

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Detalhes bibliográficos
Main Authors: Aratani, Yasuaki, Koyama, Hideki, Nyui, Sei-ichiro, Suzuki, Kazuo, Kura, Fumiaki, Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96534/
https://ncbi.nlm.nih.gov/pubmed/10085024
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