The p47(phox−/−) Mouse Model of Chronic Granulomatous Disease Has Normal Granuloma Formation and Cytokine Responses to Mycobacterium avium and Schistosoma mansoni Eggs

Chronic granulomatous disease (CGD) is a genetic disorder of NADPH oxidase in which phagocytes are defective in generating reactive oxidants. CGD patients suffer from recurrent infections and exuberant and persistent tissue granuloma formation. We hypothesized that abnormal granulomata in CGD may re...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Segal, Brahm H., Doherty, T. Mark, Wynn, Thomas A., Cheever, Allen W., Sher, Alan, Holland, Steven M.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1999
Pynciau:	Host Response and Inflammation
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96510/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10085000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.4.1659-1665.1999
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