The p47(phox−/−) Mouse Model of Chronic Granulomatous Disease Has Normal Granuloma Formation and Cytokine Responses to Mycobacterium avium and Schistosoma mansoni Eggs

Chronic granulomatous disease (CGD) is a genetic disorder of NADPH oxidase in which phagocytes are defective in generating reactive oxidants. CGD patients suffer from recurrent infections and exuberant and persistent tissue granuloma formation. We hypothesized that abnormal granulomata in CGD may re...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Segal, Brahm H., Doherty, T. Mark, Wynn, Thomas A., Cheever, Allen W., Sher, Alan, Holland, Steven M.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1999
Matèries:	Host Response and Inflammation
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96510/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10085000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.4.1659-1665.1999
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