Febrile-Range Temperature Modifies Early Systemic Tumor Necrosis Factor Alpha Expression in Mice Challenged with Bacterial Endotoxin

Fever improves survival in acute infections, but the effects of increased core temperature on host defenses are poorly understood. Tumor necrosis factor alpha (TNF-α) is an early activator of host defenses and a major endogenous pyrogen. TNF-α expression is essential for survival in bacterial infect...

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Autors principals: Jiang, Qingqi, DeTolla, Louis, van Rooijen, Nico, Singh, Ishwar S., Fitzgerald, Bridget, Lipsky, Michael M., Kane, Andrew S., Cross, Alan S., Hasday, Jeffrey D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96494/
https://ncbi.nlm.nih.gov/pubmed/10084984
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