Febrile-Range Temperature Modifies Early Systemic Tumor Necrosis Factor Alpha Expression in Mice Challenged with Bacterial Endotoxin

Fever improves survival in acute infections, but the effects of increased core temperature on host defenses are poorly understood. Tumor necrosis factor alpha (TNF-α) is an early activator of host defenses and a major endogenous pyrogen. TNF-α expression is essential for survival in bacterial infect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Qingqi, DeTolla, Louis, van Rooijen, Nico, Singh, Ishwar S., Fitzgerald, Bridget, Lipsky, Michael M., Kane, Andrew S., Cross, Alan S., Hasday, Jeffrey D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96494/
https://ncbi.nlm.nih.gov/pubmed/10084984
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