Febrile-Range Temperature Modifies Early Systemic Tumor Necrosis Factor Alpha Expression in Mice Challenged with Bacterial Endotoxin

Fever improves survival in acute infections, but the effects of increased core temperature on host defenses are poorly understood. Tumor necrosis factor alpha (TNF-α) is an early activator of host defenses and a major endogenous pyrogen. TNF-α expression is essential for survival in bacterial infect...

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Main Authors: Jiang, Qingqi, DeTolla, Louis, van Rooijen, Nico, Singh, Ishwar S., Fitzgerald, Bridget, Lipsky, Michael M., Kane, Andrew S., Cross, Alan S., Hasday, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC96494/
https://ncbi.nlm.nih.gov/pubmed/10084984
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