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Comparative Virulence of Streptococcus pneumoniae Strains with Insertion-Duplication, Point, and Deletion Mutations in the Pneumolysin Gene

Pneumolysin is a 471-amino-acid toxin produced by Streptococcus pneumoniae which has both cytolytic and complement activation properties. We have constructed a derivative of the type 2 S. pneumoniae strain D39 in which the portion of the pneumolysin gene encoding amino acids 55 to 437 has been delet...

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מידע ביבליוגרפי
Main Authors: Berry, Anne M., Ogunniyi, A. David, Miller, David C., Paton, James C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 1999
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC96416/
https://ncbi.nlm.nih.gov/pubmed/9916120
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