Therapy with a Combination of Low Doses of Interleukin 12 and Chloroquine Completely Cures Blood-Stage Malaria, Prevents Severe Anemia, and Induces Immunity to Reinfection

The immunoregulatory cytokine interleukin 12 (IL-12) induces host resistance against experimental malaria. In this study, we tested the feasibility of using IL-12 in combination with chloroquine (CQ) to rescue susceptible A/J mice from lethal blood-stage Plasmodium chabaudi AS infection. Combined tr...

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Bibliografski detalji

Izdano u:	Infect Immun
Glavni autori:	Mohan, Karkada, Sam, Hakeem, Stevenson, Mary M.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Fungal and Parasitic Infections
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9916053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.2.513-519.1999
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