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Generation of Multinucleated Giant Cells In Vitro by Culture of Human Monocytes with Mycobacterium bovis BCG in Combination with Cytokine-Containing Supernatants

Multinucleated giant cells (MGC), a characteristic feature of tuberculous granulomas, form by fusion of monocytes or macrophages, but little is known about the mechanism of the fusion process itself. Several studies report an indirect effect of mycobacteria, i.e., induction of a soluble lymphocyte-d...

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Vydáno v:Infect Immun
Hlavní autoři: Gasser, Annette, Möst, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96322/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864241/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.1.395-402.1999
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