Generation of Multinucleated Giant Cells In Vitro by Culture of Human Monocytes with Mycobacterium bovis BCG in Combination with Cytokine-Containing Supernatants

Multinucleated giant cells (MGC), a characteristic feature of tuberculous granulomas, form by fusion of monocytes or macrophages, but little is known about the mechanism of the fusion process itself. Several studies report an indirect effect of mycobacteria, i.e., induction of a soluble lymphocyte-d...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Gasser, Annette, Möst, Johannes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.1.395-402.1999
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