Up-Regulation of CD40 Ligand and Induction of a Th2 Response in Children Immunized with Pneumococcal Polysaccharide Vaccines

We wished to determine whether pneumococcal polysaccharide antigens induce mRNA expression of CD40 ligand (CD40L) and Th1 or Th2 cytokines in unimmunized individuals in vitro and whether immunization with the 23-valent pneumococcal polysaccharide vaccine induces changes in CD40L and cytokine mRNA ex...

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Bibliografiske detaljer
Main Authors: Leiva, Lily E., Butler, Boyd, Hempe, James, Ortigas, Alejandro P., Sorensen, Ricardo U.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cellular Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96042/
https://ncbi.nlm.nih.gov/pubmed/11238201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.2.233-240.2001
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