Up-Regulation of CD40 Ligand and Induction of a Th2 Response in Children Immunized with Pneumococcal Polysaccharide Vaccines

We wished to determine whether pneumococcal polysaccharide antigens induce mRNA expression of CD40 ligand (CD40L) and Th1 or Th2 cytokines in unimmunized individuals in vitro and whether immunization with the 23-valent pneumococcal polysaccharide vaccine induces changes in CD40L and cytokine mRNA ex...

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Detalhes bibliográficos
Main Authors: Leiva, Lily E., Butler, Boyd, Hempe, James, Ortigas, Alejandro P., Sorensen, Ricardo U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cellular Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96042/
https://ncbi.nlm.nih.gov/pubmed/11238201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.2.233-240.2001
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