Clonal Analysis of the Human B-Cell Repertoire Using a Heteromobility Assay
A heteromobility duplex tracking assay was developed to analyze B-cell clonality. The assay was based on the genetic variability of B-cell immunoglobulin (Ig) sequences. Binding of amplified (Ig) sequences to a single-stranded radiolabeled Ig DNA probe resulted in the formation of heteroduplexes. Th...
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| Udgivet i: | Clin Diagn Lab Immunol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.3.507-509.2000 |
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