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Clonal Analysis of the Human B-Cell Repertoire Using a Heteromobility Assay

A heteromobility duplex tracking assay was developed to analyze B-cell clonality. The assay was based on the genetic variability of B-cell immunoglobulin (Ig) sequences. Binding of amplified (Ig) sequences to a single-stranded radiolabeled Ig DNA probe resulted in the formation of heteroduplexes. Th...

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Detalhes bibliográficos
Publicado no:Clin Diagn Lab Immunol
Autor principal: Tewari, Deepanker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.3.507-509.2000
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