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Characterization of Specific Immune Responses of Mice Inoculated with Recombinant Vaccinia Virus Expressing an 18-Kilodalton Outer Membrane Protein of Brucella abortus

Using the shuttle vector pMCO2 and the vaccinia virus wild-type WR strain, we constructed a recombinant virus expressing an 18-kDa outer membrane protein of Brucella abortus. BALB/c mice inoculated with this virus produced 18-kDa protein-specific antibodies, mostly of immunoglobulin G2a isotype, and...

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Autores principales: Vemulapalli, Ramesh, Cravero, Silvio, Calvert, Christine L., Toth, Thomas E., Sriranganathan, Nammalwar, Boyle, Stephen M., Rossetti, Osvaldo L., Schurig, Gerhardt G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC95834/
https://ncbi.nlm.nih.gov/pubmed/10618289
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