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Selection and Characterization of Escherichia coli Variants Capable of Growth on an Otherwise Toxic Tryptophan Analogue

Escherichia coli isolates that were tolerant of incorporation of high proportions of 4-fluorotryptophan were evolved by serial growth. The resultant strain still preferred tryptophan for growth but showed improved growth relative to the parental strain on other tryptophan analogues. Evolved clones f...

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Autores principales: Bacher, Jamie M., Ellington, Andrew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC95426/
https://ncbi.nlm.nih.gov/pubmed/11514527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5414-5425.2001
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