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Membrane Interaction of Escherichia coli Hemolysin: Flotation and Insertion-Dependent Labeling by Phospholipid Vesicles

The 1,024-amino-acid acylated hemolysin of Escherichia coli subverts host cell functions and causes cell lysis. Both activities require insertion of the toxin into target mammalian cell membranes. To identify directly the principal toxin sequences dictating membrane binding and insertion, we assayed...

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Main Authors: Hyland, Caroline, Vuillard, Laurent, Hughes, Colin, Koronakis, Vassilis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC95420/
https://ncbi.nlm.nih.gov/pubmed/11514521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5364-5370.2001
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