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Membrane Interaction of Escherichia coli Hemolysin: Flotation and Insertion-Dependent Labeling by Phospholipid Vesicles

The 1,024-amino-acid acylated hemolysin of Escherichia coli subverts host cell functions and causes cell lysis. Both activities require insertion of the toxin into target mammalian cell membranes. To identify directly the principal toxin sequences dictating membrane binding and insertion, we assayed...

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Detalhes bibliográficos
Main Authors: Hyland, Caroline, Vuillard, Laurent, Hughes, Colin, Koronakis, Vassilis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95420/
https://ncbi.nlm.nih.gov/pubmed/11514521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5364-5370.2001
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