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Virulence Plasmid-Borne spvB and spvC Genes Can Replace the 90-Kilobase Plasmid in Conferring Virulence to Salmonella enterica Serovar Typhimurium in Subcutaneously Inoculated Mice

In a mouse model of systemic infection, the spv genes carried on the Salmonella enterica serovar Typhimurium virulence plasmid increase the replication rate of salmonellae in host cells of the reticuloendothelial system, most likely within macrophages. A nonpolar deletion in the spvB gene greatly de...

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Autors principals: Matsui, Hidenori, Bacot, Christopher M., Garlington, Wendy A., Doyle, Thomas J., Roberts, Steve, Gulig, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC95362/
https://ncbi.nlm.nih.gov/pubmed/11443102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.15.4652-4658.2001
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