Virulence Plasmid-Borne spvB and spvC Genes Can Replace the 90-Kilobase Plasmid in Conferring Virulence to Salmonella enterica Serovar Typhimurium in Subcutaneously Inoculated Mice

In a mouse model of systemic infection, the spv genes carried on the Salmonella enterica serovar Typhimurium virulence plasmid increase the replication rate of salmonellae in host cells of the reticuloendothelial system, most likely within macrophages. A nonpolar deletion in the spvB gene greatly de...

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Main Authors: Matsui, Hidenori, Bacot, Christopher M., Garlington, Wendy A., Doyle, Thomas J., Roberts, Steve, Gulig, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Genetics and Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC95362/
https://ncbi.nlm.nih.gov/pubmed/11443102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.15.4652-4658.2001
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