FosB, a Cysteine-Dependent Fosfomycin Resistance Protein under the Control of ς(W), an Extracytoplasmic-Function ς Factor in Bacillus subtilis

We demonstrate that the Bacillus subtilis fosB(yndN) gene encodes a fosfomycin resistance protein. Expression of fosB requires ς(W), and both fosB and sigW mutants are fosfomycin sensitive. FosB is a metallothiol transferase related to the FosA class of Mn(2+)-dependent glutathione transferases but...

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Bibliografiska uppgifter
Huvudupphovsmän: Cao, Min, Bernat, Bryan A., Wang, Zhepeng, Armstrong, Richard N., Helmann, John D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Genetics and Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC95149/
https://ncbi.nlm.nih.gov/pubmed/11244082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.7.2380-2383.2001
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