FosB, a Cysteine-Dependent Fosfomycin Resistance Protein under the Control of ς(W), an Extracytoplasmic-Function ς Factor in Bacillus subtilis

We demonstrate that the Bacillus subtilis fosB(yndN) gene encodes a fosfomycin resistance protein. Expression of fosB requires ς(W), and both fosB and sigW mutants are fosfomycin sensitive. FosB is a metallothiol transferase related to the FosA class of Mn(2+)-dependent glutathione transferases but...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Cao, Min, Bernat, Bryan A., Wang, Zhepeng, Armstrong, Richard N., Helmann, John D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11244082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.7.2380-2383.2001
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