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FosB, a Cysteine-Dependent Fosfomycin Resistance Protein under the Control of ς(W), an Extracytoplasmic-Function ς Factor in Bacillus subtilis
We demonstrate that the Bacillus subtilis fosB(yndN) gene encodes a fosfomycin resistance protein. Expression of fosB requires ς(W), and both fosB and sigW mutants are fosfomycin sensitive. FosB is a metallothiol transferase related to the FosA class of Mn(2+)-dependent glutathione transferases but...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC95149/ https://ncbi.nlm.nih.gov/pubmed/11244082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.7.2380-2383.2001 |
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