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Preferential Cleavage of Degradative Intermediates of rpsT mRNA by the Escherichia coli RNA Degradosome

RNase E, the principal RNase capable of initiating mRNA decay, preferentially attacks 5′-monophosphorylated over 5′-triphosphorylated substrates. Site-specific cleavage in vitro of the rpsT mRNA by RNase H directed by chimeric 2′-O-methyl oligonucleotides was employed to create truncated RNAs which...

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Bibliografiset tiedot
Päätekijät: Spickler, Catherine, Stronge, Victoria, Mackie, George A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC94981/
https://ncbi.nlm.nih.gov/pubmed/11208812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.3.1106-1109.2001
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