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Genetic and Biochemical Characterization of a Novel umuD Mutation: Insights into a Mechanism for UmuD Self-Cleavage

Most translesion DNA synthesis (TLS) in Escherichia coli is dependent upon the products of the umuDC genes, which encode a DNA polymerase, DNA polymerase V, with the unique ability to replicate over a variety of DNA lesions, including cyclobutane dimers and abasic sites. The UmuD protein is activate...

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Detalhes bibliográficos
Main Authors: Sutton, Mark D., Kim, Melanie, Walker, Graham C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC94884/
https://ncbi.nlm.nih.gov/pubmed/11114935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.1.347-357.2001
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