N-Acetyl-1-d-myo-Inosityl-2-Amino-2-Deoxy-α-d-Glucopyranoside Deacetylase (MshB) Is a Key Enzyme in Mycothiol Biosynthesis

Mycothiol is a novel thiol produced only by actinomycetes and is the major low-molecular-weight thiol in mycobacteria. Mycothiol was previously shown to be synthesized from 1-d-myo-inosityl-2-amino-2-deoxy-α-d-glucopyranoside by ligation with cysteine followed by acetylation. A novel mycothiol-depen...

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Pubblicato in:	J Bacteriol
Autori principali:	Newton, Gerald L., Av-gay, Yossef, Fahey, Robert C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Physiology and Metabolism
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11092856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.24.6958-6963.2000
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