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N-Acetyl-1-d-myo-Inosityl-2-Amino-2-Deoxy-α-d-Glucopyranoside Deacetylase (MshB) Is a Key Enzyme in Mycothiol Biosynthesis

Mycothiol is a novel thiol produced only by actinomycetes and is the major low-molecular-weight thiol in mycobacteria. Mycothiol was previously shown to be synthesized from 1-d-myo-inosityl-2-amino-2-deoxy-α-d-glucopyranoside by ligation with cysteine followed by acetylation. A novel mycothiol-depen...

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Autors principals: Newton, Gerald L., Av-gay, Yossef, Fahey, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC94821/
https://ncbi.nlm.nih.gov/pubmed/11092856
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