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N-Acetyl-1-d-myo-Inosityl-2-Amino-2-Deoxy-α-d-Glucopyranoside Deacetylase (MshB) Is a Key Enzyme in Mycothiol Biosynthesis

Mycothiol is a novel thiol produced only by actinomycetes and is the major low-molecular-weight thiol in mycobacteria. Mycothiol was previously shown to be synthesized from 1-d-myo-inosityl-2-amino-2-deoxy-α-d-glucopyranoside by ligation with cysteine followed by acetylation. A novel mycothiol-depen...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Newton, Gerald L., Av-gay, Yossef, Fahey, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94821/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11092856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.24.6958-6963.2000
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