Defects in d-Alanyl-Lipoteichoic Acid Synthesis in Streptococcus mutans Results in Acid Sensitivity

In the cariogenic organism, Streptococcus mutans, low pH induces an acid tolerance response (ATR). To identify acid-regulated proteins comprising the ATR, transposon mutagenesis with the thermosensitive plasmid pGh9:ISS1 was used to produce clones that were able to grow at neutral pH, but not in med...

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Autori principali: Boyd, David A., Cvitkovitch, Dennis G., Bleiweis, Arnold S., Kiriukhin, Michael Y., Debabov, Dmitri V., Neuhaus, Francis C., Hamilton, Ian R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Physiology and Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC94739/
https://ncbi.nlm.nih.gov/pubmed/11029425
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