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Defects in d-Alanyl-Lipoteichoic Acid Synthesis in Streptococcus mutans Results in Acid Sensitivity

In the cariogenic organism, Streptococcus mutans, low pH induces an acid tolerance response (ATR). To identify acid-regulated proteins comprising the ATR, transposon mutagenesis with the thermosensitive plasmid pGh9:ISS1 was used to produce clones that were able to grow at neutral pH, but not in med...

Ausführliche Beschreibung

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Boyd, David A., Cvitkovitch, Dennis G., Bleiweis, Arnold S., Kiriukhin, Michael Y., Debabov, Dmitri V., Neuhaus, Francis C., Hamilton, Ian R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Physiology and Metabolism
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029425/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.21.6055-6065.2000
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