Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

The processing of DNA double-strand breaks is a critical event in nucleic acid metabolism. This is evidenced by the severity of phenotypes associated with deficiencies in this process in multiple organisms. The core component involved in double-strand break repair in eukaryotic cells is the Mre11-Ra...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Hopfner, Karl-Peter, Karcher, Annette, Shin, David, Fairley, Cecilia, Tainer, John A., Carney, James P.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Genetics and Molecular Biology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029422/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.21.6036-6041.2000
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