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AcrD of Escherichia coli Is an Aminoglycoside Efflux Pump

AcrD, a transporter belonging to the resistance-nodulation-division family, was shown to participate in the efflux of aminoglycosides. Deletion of the acrD gene decreased the MICs of amikacin, gentamicin, neomycin, kanamycin, and tobramycin by a factor of two to eight, and ΔacrD cells accumulated hi...

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Main Authors: Rosenberg, Emiko Y., Ma, Dzwokai, Nikaido, Hiroshi
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC94475/
https://ncbi.nlm.nih.gov/pubmed/10692383
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