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Molecular Basis for the Temperature Sensitivity of Escherichia coli pth(Ts)

The gene pth, encoding peptidyl-tRNA hydrolase (Pth), is essential for protein synthesis and viability of Escherichia coli. Two pth mutants have been studied in depth: a pth(Ts) mutant isolated as temperature sensitive and a pth(rap) mutant selected as nonpermissive for bacteriophage λ vegetative gr...

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Bibliographic Details
Main Authors: Cruz-Vera, L. Rogelio, Toledo, Ivonne, Hernández-Sánchez, Javier, Guarneros, Gabriel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC94448/
https://ncbi.nlm.nih.gov/pubmed/10692356
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