Suppression of Temperature-Sensitive Chromosome Replication of an Escherichia coli dnaX(Ts) Mutant by Reduction of Initiation Efficiency

Temperature sensitivity of DNA polymerization and growth of a dnaX(Ts) mutant is suppressible at 39 to 40°C by mutations in the initiator gene, dnaA. These suppressor mutations concomitantly cause initiation inhibition at 20°C and have been designated Cs,Sx to indicate both phenotypic characteristic...

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Autores principales: Blinkova, Alexandra, Hermandson, Mary Jo, Walker, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Genetics and Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC156227/
https://ncbi.nlm.nih.gov/pubmed/12775696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.12.3583-3595.2003
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