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Evolution of Drug Resistance in Experimental Populations of Candida albicans

Adaptation to inhibitory concentrations of the antifungal agent fluconazole was monitored in replicated experimental populations founded from a single, drug-sensitive cell of the yeast Candida albicans and reared over 330 generations. The concentration of fluconazole was maintained at twice the MIC...

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Main Authors: Cowen, Leah E., Sanglard, Dominique, Calabrese, David, Sirjusingh, Caroline, Anderson, James B., Kohn, Linda M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC94447/
https://ncbi.nlm.nih.gov/pubmed/10692355
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