Reduced Flux through the Purine Biosynthetic Pathway Results in an Increased Requirement for Coenzyme A in Thiamine Synthesis in Salmonella enterica Serovar Typhimurium

Work presented here establishes a connection between cellular coenzyme A (CoA) levels and thiamine biosynthesis in Salmonella enterica serovar Typhimurium. Prior work showed that panE mutants (panE encodes ketopantoate reductase) had a conditional requirement for thiamine or pantothenate. Data prese...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Frodyma, Michael, Rubio, Aileen, Downs, D. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10613889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.1.236-240.2000
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