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Reduced Flux through the Purine Biosynthetic Pathway Results in an Increased Requirement for Coenzyme A in Thiamine Synthesis in Salmonella enterica Serovar Typhimurium

Work presented here establishes a connection between cellular coenzyme A (CoA) levels and thiamine biosynthesis in Salmonella enterica serovar Typhimurium. Prior work showed that panE mutants (panE encodes ketopantoate reductase) had a conditional requirement for thiamine or pantothenate. Data prese...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Frodyma, Michael, Rubio, Aileen, Downs, D. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10613889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.1.236-240.2000
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