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Identification of Metal Ligands in the Clostridium histolyticum ColH Collagenase

A Clostridium histolyticum 116-kDa collagenase has an H(415)EXXH motif but not the third zinc ligand, as found in already characterized zinc metalloproteinases. To identify its catalytic site, we mutated the codons corresponding to the three conserved residues in the motif to other amino acid residu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Bacteriol
Prif Awduron: Jung, Chang-Min, Matsushita, Osamu, Katayama, Seiichi, Minami, Junzaburo, Sakurai, Jun, Okabe, Akinobu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10217773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.9.2816-2822.1999
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