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Identification of Metal Ligands in the Clostridium histolyticum ColH Collagenase

A Clostridium histolyticum 116-kDa collagenase has an H(415)EXXH motif but not the third zinc ligand, as found in already characterized zinc metalloproteinases. To identify its catalytic site, we mutated the codons corresponding to the three conserved residues in the motif to other amino acid residu...

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Autores principales: Jung, Chang-Min, Matsushita, Osamu, Katayama, Seiichi, Minami, Junzaburo, Sakurai, Jun, Okabe, Akinobu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC93724/
https://ncbi.nlm.nih.gov/pubmed/10217773
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