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Aspartate Kinase-Independent Lysine Synthesis in an Extremely Thermophilic Bacterium, Thermus thermophilus: Lysine Is Synthesized via α-Aminoadipic Acid Not via Diaminopimelic Acid

An aspartate kinase-deficient mutant of Thermus thermophilus, AK001, was constructed. The mutant strain did not grow in a minimal medium, suggesting that T. thermophilus contains a single aspartate kinase. Growth of the mutant strain was restored by addition of both threonine and methionine, while a...

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Udgivet i:J Bacteriol
Principais autores: Kobashi, Nobuyuki, Nishiyama, Makoto, Tanokura, Masaru
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Physiology and Metabolism
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.6.1713-1718.1999
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