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Aspartate Kinase-Independent Lysine Synthesis in an Extremely Thermophilic Bacterium, Thermus thermophilus: Lysine Is Synthesized via α-Aminoadipic Acid Not via Diaminopimelic Acid

An aspartate kinase-deficient mutant of Thermus thermophilus, AK001, was constructed. The mutant strain did not grow in a minimal medium, suggesting that T. thermophilus contains a single aspartate kinase. Growth of the mutant strain was restored by addition of both threonine and methionine, while a...

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Detalhes bibliográficos
Main Authors: Kobashi, Nobuyuki, Nishiyama, Makoto, Tanokura, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC93567/
https://ncbi.nlm.nih.gov/pubmed/10074061
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