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Inhibition of Translation and Cell Growth by Minigene Expression

A random five-codon gene library was used to isolate minigenes whose expression causes cell growth arrest. Eight different deleterious minigenes were isolated, five of which had in-frame stop codons; the predicted expressed peptides ranged in size from two to five amino acids. Mutational analysis de...

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Tenson, Tanel, Herrera, Jesús Vega, Kloss, Patricia, Guarneros, Gabriel, Mankin, Alexander S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.5.1617-1622.1999
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