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Sequestration of specific tRNA species cognate to the last sense codon of an overproduced gratuitous protein

High-level expression of non-functional model proteins, derived from elongation factor EF-Tu by the deletion of an essential domain, greatly inhibits the growth of Escherichia coli partly deficient in peptidyl-tRNA hydrolase. High-level expression in wild-type cells has little effect on growth. The...

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Autors principals: Menez, Jeanne, Heurgué-Hamard, Valérie, Buckingham, Richard H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115180/
https://ncbi.nlm.nih.gov/pubmed/11095683
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