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Mutations in the Listerial proB Gene Leading to Proline Overproduction: Effects on Salt Tolerance and Murine Infection

The observed sensitivity of Listeria monocytogenes to the toxic proline analogue l-azetidine-2-carboxylic acid (AZ) suggested that proline synthesis in Listeria may be regulated by feedback inhibition of γ-glutamyl kinase (GK), the first enzyme of the proline biosynthesis pathway, encoded by the pro...

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Udgivet i:Appl Environ Microbiol
Principais autores: Sleator, Roy D., Gahan, Cormac G. M., Hill, Colin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Physiology and Biotechnology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11571156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.67.10.4560-4565.2001
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