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Mutations in the Listerial proB Gene Leading to Proline Overproduction: Effects on Salt Tolerance and Murine Infection

The observed sensitivity of Listeria monocytogenes to the toxic proline analogue l-azetidine-2-carboxylic acid (AZ) suggested that proline synthesis in Listeria may be regulated by feedback inhibition of γ-glutamyl kinase (GK), the first enzyme of the proline biosynthesis pathway, encoded by the pro...

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Autors principals: Sleator, Roy D., Gahan, Cormac G. M., Hill, Colin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC93203/
https://ncbi.nlm.nih.gov/pubmed/11571156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.10.4560-4565.2001
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