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The Phosphinomethylmalate Isomerase Gene pmi, Encoding an Aconitase-Like Enzyme, Is Involved in the Synthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes

Streptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricin tripeptide (PTT). In the postulated biosynthetic pathway, one reaction, the isomerization of phosphinomethylmalate, resembles the aconitase reaction of the tricarboxylic acid (TCA) cycle. It was speculated that this reacti...

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Autori principali: Heinzelmann, E., Kienzlen, G., Kaspar, S., Recktenwald, J., Wohlleben, W., Schwartz, D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC93061/
https://ncbi.nlm.nih.gov/pubmed/11472937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.8.3603-3609.2001
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