The Phosphinomethylmalate Isomerase Gene pmi, Encoding an Aconitase-Like Enzyme, Is Involved in the Synthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes

Streptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricin tripeptide (PTT). In the postulated biosynthetic pathway, one reaction, the isomerization of phosphinomethylmalate, resembles the aconitase reaction of the tricarboxylic acid (TCA) cycle. It was speculated that this reacti...

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Autores principales: Heinzelmann, E., Kienzlen, G., Kaspar, S., Recktenwald, J., Wohlleben, W., Schwartz, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Genetics and Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC93061/
https://ncbi.nlm.nih.gov/pubmed/11472937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.8.3603-3609.2001
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