The Phosphinomethylmalate Isomerase Gene pmi, Encoding an Aconitase-Like Enzyme, Is Involved in the Synthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes

Streptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricin tripeptide (PTT). In the postulated biosynthetic pathway, one reaction, the isomerization of phosphinomethylmalate, resembles the aconitase reaction of the tricarboxylic acid (TCA) cycle. It was speculated that this reacti...

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Main Authors: Heinzelmann, E., Kienzlen, G., Kaspar, S., Recktenwald, J., Wohlleben, W., Schwartz, D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Genetics and Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC93061/
https://ncbi.nlm.nih.gov/pubmed/11472937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.8.3603-3609.2001
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